Atsuko Kimura Selected Research

Neuroinflammatory Diseases

1/2022	ASK1 signaling regulates phase-specific glial interactions during neuroinflammation.
1/2020	Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.
12/2017	The Renin-Angiotensin System Regulates Neurodegeneration in a Mouse Model of Optic Neuritis.
1/2017	Valproic acid and ASK1 deficiency ameliorate optic neuritis and neurodegeneration in an animal model of multiple sclerosis.

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Atsuko Kimura Research Topics

Disease

13	Retinal Degeneration 01/2019 - 11/2009
12	Glaucoma 09/2020 - 11/2014
9	Low Tension Glaucoma 03/2022 - 11/2009
5	Optic Nerve Injuries 09/2020 - 10/2014
5	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2020 - 04/2011
5	Optic Neuritis (Retrobulbar Neuritis) 12/2017 - 04/2011
4	Neuroinflammatory Diseases 01/2022 - 01/2017
4	Multiple Sclerosis 01/2020 - 04/2011
4	Vision Disorders (Hemeralopia) 12/2017 - 04/2015
3	Demyelinating Diseases (Demyelinating Disease) 12/2017 - 04/2011
3	Mood Disorders (Mood Disorder) 03/2015 - 07/2009
2	Brain Infarction 01/2017 - 01/2017
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2017 - 01/2017
2	Epilepsy (Aura) 03/2015 - 02/2015
2	Migraine Disorders (Migraine) 03/2015 - 02/2015
2	Neuralgia (Stump Neuralgia) 03/2015 - 02/2015
1	Macular Degeneration (Age-Related Maculopathy) 03/2022
1	Erythema 05/2021
1	Retinal Diseases 09/2016
1	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2016
1	Neoplasms (Cancer) 11/2014
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 11/2014
1	Alzheimer Disease (Alzheimer's Disease) 11/2014
1	Micrognathism 04/2011
1	Mental Disorders (Mental Disorder) 07/2009
1	Feeding and Eating Disorders (Eating Disorder) 07/2009
1	Anxiety Disorders (Anxiety Disorder) 07/2009

Drug/Important Bio-Agent (IBA)

8	Retinaldehyde (Retinal)IBA 03/2022 - 10/2014
6	Neuroprotective AgentsIBA 01/2018 - 03/2015
5	Pharmaceutical PreparationsIBA 01/2019 - 02/2015
4	Amino Acid Transport System X-AG (Glutamate Transporter)IBA 03/2022 - 01/2019
4	Excitatory Amino AcidsIBA 01/2019 - 07/2015
4	Valproic Acid (Depakote)FDA LinkGeneric 01/2017 - 02/2015
3	MAP Kinase Kinase Kinase 5IBA 01/2022 - 01/2017
3	AntioxidantsIBA 09/2020 - 04/2011
3	Glutamic Acid (Glutamate)FDA Link 09/2020 - 02/2011
3	SpermidineIBA 01/2017 - 04/2011
2	MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA 01/2022 - 03/2017
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 11/2014
2	K-115IBA 01/2020 - 01/2018
2	Ophthalmic Solutions (Eye Drops)IBA 01/2019 - 04/2015
2	N-Methylaspartate (NMDA)IBA 01/2019 - 03/2015
2	EdaravoneIBA 01/2017 - 01/2017
2	Free Radical ScavengersIBA 01/2017 - 01/2017
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 09/2016 - 12/2015
1	Peptides (Polypeptides)IBA 01/2020
1	Acetylcysteine (Siran)FDA LinkGeneric 01/2019
1	LipopolysaccharidesIBA 12/2017
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 12/2017
1	candesartanIBA 12/2017
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 03/2017
1	SteroidsIBA 01/2017
1	EnzymesIBA 01/2017
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2016
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 09/2016
1	Nerve Growth Factors (Neurotrophins)IBA 09/2016
1	Nerve Growth Factor (NGF)IBA 09/2016
1	Ciliary Neurotrophic Factor (CNTF)IBA 09/2016
1	Brimonidine Tartrate (Alphagan)FDA LinkGeneric 04/2015
1	p38 Mitogen-Activated Protein KinasesIBA 10/2014
1	SB 203580IBA 10/2014
1	diacetyldichlorofluoresceinIBA 04/2011
1	Interleukin-1 (Interleukin 1)IBA 11/2009
1	LigandsIBA 07/2009
1	Neurotransmitter Agents (Neurotransmitter)IBA 07/2009
1	Antidepressive Agents (Antidepressants)IBA 07/2009
1	Anti-Anxiety Agents (Anxiolytics)IBA 07/2009
1	5-HT2C Serotonin ReceptorIBA 07/2009

Therapy/Procedure

6	Therapeutics 09/2020 - 09/2016
2	Intraperitoneal Injections 01/2017 - 02/2015
1	Blood Component Removal (Apheresis) 05/2021
1	Oral Administration 12/2017
1	Caloric Restriction 09/2016
1	Topical Administration 04/2015
1	Airway Management 04/2011